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What to Expect in Month 2 Peak nausea: Weeks 6-8 worst for most patients, especially mornings Food aversions: Foods you loved suddenly repulsive (especially meat, coffee) Early satiety: Feel full after 3-4 bites, physical discomfort if you push it Fatigue increases: Combination of medication adjustment and reduced calorie intake Bowel unpredictability: Constipation one day, diarrhea the next Mental fog: Some patients report difficulty concentrating Research from the New England Journal of Medicine on incretin therapies shows this peak-and-resolution pattern is universal across GLP-1 and GIP agonists

Vegetarian and Vegan Support: Individuals following a vegetarian or vegan lifestyle often struggle to obtain sufficient B12 from diet alone

J Clin Invest (2015) 125:106980

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Endoplasmic Reticulum Stress in Disease Pathogenesis. Annual Review of Pathology, vol